An economic review of the national screening policy to prevent thalassemia major in Iran

This Paper is to describe the economic burden of thalassemia as a major health problem in thalassemia belt countries like Iran. Great emphasis is placed on prenatal diagnosis to prevent the disease, as the “economic” solution from a health care policy viewpoint. The alternative method of the current screening program in Iran is outlined and discussed especially with respect to the “cost-effectiveness” issue, along with some pitfalls of the general plan and the techniques under use. Further follow-up of program after such refinement is advised, and especially the provision of a working option of prenatal diagnosis to carrier couples is recommended.